Wednesday, January 25, 2006

Viread and PreP

Hat tip to Reader "C" for the reference to this article on Viread: "Protect or Disinhibit?" from the New York Times. Jon Cohen writes about Project T, an international research project being underwritten by the CDC, NIH, and Bill and Melinda Gates Foundation. Project T is investigating whether tenofovir (brand name Viread) will work as pre-exposure prophylaxis (PreP) for HIV. If so, we will have yet another tool in our belt to prevent HIV.

Sounds good enough, but there are some additional concerns. "Disinhibition" is a new term for me, but it may become a favorite, along with "disinformation." Both terms apply, in this context, to something that leads folks away from the use of condoms to prevent the spread of HIV. Disinformation, in this context, would be false information that some folks are spreading about the effectiveness of condoms. Disinhibition, in this case, would be reliance on a pill for prophylaxis to the exclusion of barrier protection. An assumption of the research, it would seem, is that tenofovir would be used in tandem with condoms. A concern with the research project is that condoms would be abandoned for tenofovir. tenofovir - condoms. I would say "You do the math," but, Cohen has further added to my education by introducing me to the 3 V's. [sigh]

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